منابع مشابه
Phosphate and FGF-23
Fibroblast growth factor (FGF)-23 is probably the most important regulator of serum phosphate and calcitriol (1,25(OH)₂D₃) levels. It is secreted by osteocytes and osteoblasts in response to oral phosphate loading or increased serum 1,25(OH)₂D₃ levels. In human chronic kidney disease (CKD), plasma FGF-23 appears to be a sensitive biomarker of abnormal renal phosphate handling, as FGF-23 levels ...
متن کاملFGF-23 and Left Ventricular Hypertrophy
Submit Manuscript | http://medcraveonline.com cardiovascular health [1]. Among these FGFs, notably FGF-21 has shown cardio-protective effects such as improving lipoprotein profile, endothelial dysfunction and reducing plaque formation [1]. FGF-23; member of the FGF19 subfamily shows the highest degree of homology with FGF-21 [2,3]. However, contrary to FGF21, elevated levels of the bone-derived...
متن کاملPTH, FGF-23 and early CKD.
Patients with early CKD (GFR > 30 ml/min per 1.73 m2) do not usually have changes in the serum calcium and phosphate concentration. PTH may be minimally increased and more recent publications have shown that the phosphaturic hormone, FGF-23, is clearly increased. Thus in early CKD, serum levels of phosphate and calcium are maintained within normal levels because hormonal changes compensate for ...
متن کاملQuantification of the roles of trabecular microarchitecture and trabecular type in determining the elastic modulus of human trabecular bone.
UNLABELLED The roles of microarchitecture and types of trabeculae in determining elastic modulus of trabecular bone have been studied in microCT images of 29 trabecular bone samples by comparing their Young's moduli calculated by finite element analysis (FEA) with different trabecular type-specific reconstructions. The results suggest that trabecular plates play an essential role in determining...
متن کاملLong range node-strut analysis of trabecular bone microarchitecture.
PURPOSE We present a new morphometric measure of trabecular bone microarchitecture, called mean node strength (NdStr), which is part of a newly developed approach called long range node-strut analysis. Our general aim is to describe and quantify the apparent "latticelike" microarchitecture of the trabecular bone network. METHODS Similar in some ways to the topological node-strut analysis intr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Osteoporosis International
سال: 2019
ISSN: 0937-941X,1433-2965
DOI: 10.1007/s00198-019-05123-2